By Paul J. Marangos
Read or Download Brain Receptor Methodologies. Part A: General Methods and Concepts. Amines and Acetylcholine PDF
Best general books
This publication reconsiders the elemental methods at the back of the BEM procedure and particularly assesses and validates the equations forming the final momentum concept. One a part of the e-book issues the validation, utilizing numerical fluid mechanics (CFD), of different phrases within the equations forming the momentum thought.
This is often the 1st English translation of the seminal ebook by means of Katharina Reiß and Hans Vermeer, Grundlegung einer allgemeinen Translationstheorie, first released in 1984. the 1st a part of the ebook was once written via Vermeer and explains the theoretical foundations and uncomplicated rules of skopos concept as a basic conception of translation and studying or ‘translational action’, while the second one half, penned by means of Katharina Reiß, seeks to combine her text-typological strategy, first awarded in 1971, as a ‘specific conception’ that makes a speciality of these situations during which the skopos calls for equivalence of capabilities among the resource and aim texts.
Extra info for Brain Receptor Methodologies. Part A: General Methods and Concepts. Amines and Acetylcholine
J. (1979). Life Sei. 24, 1739-1746. Hunston, D. L. (1975). Anal. Biochem. 63, 9 9 - 1 0 9 . Klotz, I. M. (1982). Science 217, 1247-1249. Kosterlitz, H. W . , Paterson, S. , and Robson, L. E. (1981). Br. J. Pharmacol. 73, 9 3 9 - 9 4 9 . Martin, W. , Eades, C. B . , Thompson, J. Α . , Huppier, R. , and Gilbert, P. E. (1976). J. Pharmacol. Exp. Ther. 197, 5 1 7 - 5 2 2 . Munson, P. J. (1981), " U s e r ' s Guide to LIGAND. A Program System for Fitting Multiple Ligand, Multiple Binding Site D a t a .
Human antrum fixed in benzoquinone vapor, three in serial sections stained for neuronspecific enolase (a) and for gastrin (b). Long arrows point to endocrine cells containing both peptide and enzyme. Other cells are clearly stained only for neuron-specific enolase, indicating the près- 51 4. The Distribution of Peripheral Regulatory Peptides A.
To determine if these ligands are binding to the same or to independent classes of receptors, competition studies using the corresponding unlabeled ligands should be performed. Complete cross-displacement should be observed if only a single receptor binding site is involved. Failure of one of the unlabeled ligands to compete or reduction of the slope of the competition curve suggests that two or more independent sites may be involved. Saturation of the same receptor with different labeled ligands should result in the same measured binding capacity.
Brain Receptor Methodologies. Part A: General Methods and Concepts. Amines and Acetylcholine by Paul J. Marangos